Uraemic optic neuropathy – a rare presentation of uraemia

Adaobi Uzoamaka Solarin, Adetola M Adesanya, Moturayo Adekunle, Alaba Oladimeji, Olusegun Henry Gbelee, Barakat Adeola Animashaun


Uraemic optic neuropathy (UON) is an acute but reversible loss of vision in patients with end-stage renal failure. Hypoperfusion of the posterior ciliary arteries, the major blood supply to the optic nerve head, results in ischaemic injury to the nerve. Anaemia, hypertension and elevated nitrogen urea level have been identified as factors contributing to optic nerve neuropathy. Toxic uraemic metabolites affect nerve conduction and their removal with dialysis results in improved vision. Optic neuropathy is a rare complication of uraemia in children. This is the first case of optic neuropathy related to uraemia in a child with end-stage renal disease in Nigeria.



uraemia; reversible blindness; haemodialysis,

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DOI: https://doi.org/10.21804/21-1-2759


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ISSN (online) 2518-4601 ISSN 2306-8205 (print). © African Association of Nephrology 2019.
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